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Abstract
Schizophrenia patients require consistent adherence to their treatment process in order to maintain stability and improve their quality of life. This study aims to examine the relationship between family support and medication adherence among patients with schizophrenia. The research was conducted at several community health centers in Lakudo District using a descriptive analytic design with a cross-sectional approach. The population consisted of family members of schizophrenia patients, and the research sample was selected using a purposive sampling technique. Family support was measured using a questionnaire, while medication adherence among schizophrenia patients was assessed using the Morisky Medication Adherence Scale. The findings indicate that many respondents experienced low levels of family support and a considerable number of patients showed non-adherence to their medication regimen. Statistical analysis using the Chi-Square test demonstrated a significant relationship between family support and medication adherence among schizophrenia patients in Lakudo District, Central Buton Regency. These results highlight the important role of family involvement in supporting patients throughout the treatment process. Strong family support can encourage patients to follow their medication schedule more consistently and contribute to better management of schizophrenia.
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Copyright (c) 2026 Haslina, Muhamad Ikhsan, Suhaeni, Budi Prasetyo

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References
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References
Ahmadi, C. H. (2015). Hubungan Dukungan Keluarga Dengan Kepatuhan Minum Obat Pada Pasien Gangguan Jiwa Di Poliklinik Rawat Jalan RSJ Provinsi Jawa Barat Tahun 2015.
Caqueo-Urizar, A., Urzua, A., Mena-Chamorro, P., & Bravo De la Fuente, J. (2021, September). Effects of adherence to pharmacological treatment on the recovery of patients with schizophrenia. In Healthcare (Vol. 9, No. 9, p. 1230). MDPI.
Deng, M., Zhai, S., Ouyang, X., Liu, Z., & Ross, B. (2022). Factors influencing medication adherence among patients with severe mental disorders from the perspective of mental health professionals. BMC psychiatry, 22(1), 22.
Dinas Kesehatan Buton Tengah. (2023). Data Pusdatin Capaian Indikator SPM Tahun 2023. Buton Tengah : Dinas Kesehatan Buton Tengah.
Febria, S.S. (2017). Dukungan Keluarga Dengan Kekambuhan Pada Pasien Skizofrenia. Akper Nabila Padang Panjang : Jln.DR.Khamarullah No.1 Busur Padang Panjang.
Hamdani, R., Hariyanto, T., & Dewi, N. (2017). Hubungan Dukungan Keluarga Dengan Tingkat Kepatuhan Minum Obat Pada Pasien Skizofrenia Di Ruang Rawat Jalan Rumah Sakit Jiwa Mutiara Sukma Provinsi NTB. Nursing News: Jurnal Ilmiah Keperawatan, 2(3).
Hsieh, W. L., Yeh, S. T., Liu, W. I., Li, I. H., Lee, S. K., & Chien, W. T. (2022). Improving medication adherence in community-dwelling patients with schizophrenia through therapeutic alliance and medication attitude: A Serial Multiple Mediation Model. Patient preference and adherence, 1017-1026.
Glick, I. D., Stekoll, A. H., & Hays, S. (2011). The role of the family and improvement in treatment maintenance, adherence, and outcome for schizophrenia. Journal of clinical psychopharmacology, 31(1), 82-85.
Lin, Y. Y., Yen, W. J., Hou, W. L., Liao, W. C., & Lin, M. L. (2022, March). Mental health nurses’ tacit knowledge of strategies for improving medication adherence for schizophrenia: A qualitative study. In Healthcare (Vol. 10, No. 3, p. 492). MDPI.
Mamang, A., Anwar, S., & Nurhayati, N. (2024). Analysis of the Relationship between Knowledge About Schizophrenia and Family Support on Medication Adherence Among Those Undergoing Repeated Treatment at Dr. Soeharto Heerdjan Mental Hospital: Analisis Hubungan antara Pengetahuan Tentang Skizofrenia dan Dukungan Keluarga terhadap Kepatuhan Minum Obat pada Pasien yang Menjalani Perawatan Berulang di Rumah Sakit Jiwa Dr. Soeharto Heerdjan. Jurnal Ilmiah Ilmu Keperawatan Indonesia, 14(02), 22-31.
Nuralita, N., & Khairunisa, D. (2022). Relationship between Family Knowledge and Compliance in Medication for Schizophrenia Outpatient at Prof. M. Ildrem Mental Hospital. Open Access Macedonian Journal of Medical Sciences, 10(T7), 130-133.
Purbaningsi., Sari, E., & Muadi. (2022). Hubungan Dukungan Keluarga Dalam Memberdayakan Penderita Skizofrenia Dengan Frekuensi Kekambuhan Penderita Skizofrenia Di Wilayah Kerja Puskesmas Sitopeng Kota Cirebon. 2(12),1063-1069.
Putra, F. A., & Sukmonowati, W. (2021). Hubungan Kepatuhan Minum Obat Dengan Tingkat Kekambuhan Pada Pasien Skizofrenia. Jurnal Ilmu Keperawatan Indonesia (JIKI), 14(1).
Rahmawati, A. N., & Maryoto, M. (2021). Hubungan antara Dukungan Keluarga dengan Kepatuhan Minum Obat pada Penderita Skizofrenia di Wilayah Kerja UPTD Puskesmas Bojongsari Kabupaten Purbalingga. 869–875.
Ratnawati, R. (2016). Hubungan Dukungan Keluarga Dengan Kepatuhan Berobat Penderita Skizofrenia.Stikes Bakti Husada Mulia Madiun
Riset Kesehatan Dasar (Riskesdas). (2018). Badan Penelitian dan Pengembangan Kesehatan Kementrian R1 tahun 2018.pdf.
Semahegn, A., Torpey, K., Manu, A., Assefa, N., Tesfaye, G., & Ankomah, A. (2020). Psychotropic medication non-adherence and its associated factors among patients with major psychiatric disorders: a systematic review and meta-analysis. Systematic reviews, 9(1), 17.
Shan, P., Zhuo, C., Lin, X., Chen, M., Ma, X., Li, R., ... & Zhang, J. (2020). Supportive family environments can improve treatment compliance, social cognition, brain activity in patients with schizophrenia–A pilot study. Psychiatry and Clinical Psychopharmacology, 30(4), 362-368.
Survei Kesehatan Indonesia. (2023). Laporan Survei Kesehatan Indonesia Tahun 2023. Kemenkes: Badan Kebijakan Pembangunan Kesehatan. Jakarta. https://www.badankebijakan.kemkes.go.id/hasil-ski-2023
Tiara, C., Pramesti, W., Pebriyani, U., & Alfarisi, R. (2020). Hubungan Konsep Dukungan Keluarga Dengan Tingkat Kekambuhan Pada Pasien Skizofrenia. Jurnal Ilmiah Kesehatan Sandi Husada, 9(1), 522–532.
Videbeck, S. L. (2020). Psychiatric-Mental Health Nursing. 8th edn. Edited by L. Gray dan D. Murphy. Philadelphia United States of America: Wolters Kluwer.
World Health Organization. (2019). Mental disorders fact sheets. World Health Organization.
